Beta-glucan is a substance found naturally in several foods,
including oats, barley, and certain mushrooms. Also found in yeasts,
beta-glucan is classified as a polysaccharide (a large molecule made up
of multiple sugar molecules). There's some evidence that beta-glucan may
offer a number of health benefits, such as stimulation of the immune system.
Benefits of Beta-Glucan Here's a look at some key study findings on the possible health benefits of beta-glucan:
In a 2004 study from Medicine and Science in Sports and Exercise, for instance, tests on mice revealed that beta-glucan may offset the negative effects of exercise-induced stress and increase the immune system's defense against upper respiratory tract infections.
Many beta-glucan supplements source their beta-glucan from substances like baker's yeast. Others contain medicinal mushrooms like shiitake and maitake (both found to be rich in beta-glucan). While research on the health effects of medicinal mushroom supplements is somewhat limited, a number of studies suggest that they can help boost immunity.
If you're considering the use of beta-glucan supplements in treatment of a chronic condition, make sure to talk to your doctor before starting your supplement regimen.
Sources:
American Cancer Society. "Maitake Mushrooms." November 2008.
Chan GC, Chan WK, Sze DM. "The effects of beta-glucan on human immune and cancer cells." J Hematol Oncol. 2009 Jun 10;2:25.
Chen J, Raymond K. "Beta-glucans in the treatment of diabetes and associated cardiovascular risks." Vasc Health Risk Manag. 2008;4(6):1265-72.
Davis JM, Murphy EA, Brown AS, Carmichael MD, Ghaffar A, Mayer EP. "Effects of oat beta-glucan on innate immunity and infection after exercise stress." Med Sci Sports Exerc. 2004 Aug;36(8):1321-7.
Othman RA, Moghadasian MH, Jones PJ. "Cholesterol-lowering effects of oat β-glucan." Nutr Rev. 2011 Jun;69(6):299-309. doi: 10.1111/j.1753-4887.2011.00401.x.
Benefits of Beta-Glucan Here's a look at some key study findings on the possible health benefits of beta-glucan:
1) Cholesterol
The beta-glucan found in oats may help keep cholesterol in check, according to a 2011 report from Nutrition Reviews. Looking at studies conducted over the previous 13 years, the report's authors determined that oat-derived beta-glucan may significantly reduce levels of total and LDL ("bad") cholesterol. On average, the authors note, daily oat consumption is associated with 5 percent and 7 percent reductions in total and LDL cholesterol levels, respectively.2) Diabetes
Beta-glucan may help manage diabetes, a 2008 research review from Vascular Health and Risk Management suggests. Analyzing previous research on beta-glucan and diabetes, the review's authors found that dietary intake of beta-glucan may help protect against diabetes-related complications by controlling blood sugar levels, lowering cholesterol, and keeping blood pressure in check.3) Cancer
Preliminary research indicates that beta-glucan may activate a number of cells and proteins that fight cancer (such as T-cells and natural killer cells). What's more, tests on animals have shown that beta-glucan may inhibit the spread of cancer cells. However, a 2009 report in the Journal of Hematology and Oncology cautions that there are "no good quality clinical trial data" for the effectiveness of beta-glucan in treating cancer.4) Immunity
Currently, there is a lack of clinical trials supporting the claim that beta-glucan can rev up the immune system and stave off colds, flu, and other types of infection. However, some preliminary research suggests that beta-glucan may strengthen the immune system and knock out viruses.In a 2004 study from Medicine and Science in Sports and Exercise, for instance, tests on mice revealed that beta-glucan may offset the negative effects of exercise-induced stress and increase the immune system's defense against upper respiratory tract infections.
Uses for Beta-Glucan
In addition to being available in foods, beta-glucan is sold in supplement form. Proponents claim that beta-glucan supplements can help with the following health problems:- allergies
- asthma
- Crohn's disease
- chronic fatigue syndrome
- diabetes
- fibromyalgia
- high cholesterol
- rheumatoid arthritis
- ulcerative colitis
Where to Find Beta-Glucan Supplements
Beta-glucan supplements are widely available for purchase online, and are also sold in many natural-food stores and in stores specializing in dietary supplements.Many beta-glucan supplements source their beta-glucan from substances like baker's yeast. Others contain medicinal mushrooms like shiitake and maitake (both found to be rich in beta-glucan). While research on the health effects of medicinal mushroom supplements is somewhat limited, a number of studies suggest that they can help boost immunity.
Safety
Although beta-glucan is generally considered safe, there's some concern that it may lower blood sugar. Therefore, people with hypoglycemia (or anyone taking medications to reduce blood sugar) should consult a physician before using beta-glucan.Using Beta-Glucan Supplements for Health
Although it's too soon to recommend beta-glucan supplements for health purposes, increasing your beta-glucan intake (by including oats, barley, and medicinal mushrooms in your diet) may help enhance your overall health.If you're considering the use of beta-glucan supplements in treatment of a chronic condition, make sure to talk to your doctor before starting your supplement regimen.
Sources:
American Cancer Society. "Maitake Mushrooms." November 2008.
Chan GC, Chan WK, Sze DM. "The effects of beta-glucan on human immune and cancer cells." J Hematol Oncol. 2009 Jun 10;2:25.
Chen J, Raymond K. "Beta-glucans in the treatment of diabetes and associated cardiovascular risks." Vasc Health Risk Manag. 2008;4(6):1265-72.
Davis JM, Murphy EA, Brown AS, Carmichael MD, Ghaffar A, Mayer EP. "Effects of oat beta-glucan on innate immunity and infection after exercise stress." Med Sci Sports Exerc. 2004 Aug;36(8):1321-7.
Othman RA, Moghadasian MH, Jones PJ. "Cholesterol-lowering effects of oat β-glucan." Nutr Rev. 2011 Jun;69(6):299-309. doi: 10.1111/j.1753-4887.2011.00401.x.
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